Pharmacological effects of flufenicol

Flufenicol is an antibiotic drug that produces a broad-spectrum antibacterial effect by inhibiting peptidyltransferase activity, with a wide antibacterial spectrum, including various Gram positive, negative bacteria, and mycoplasma. Sensitive bacteria include Haemophilus bacteria, Shigella dysentery, Salmonella, Escherichia coli, pneumococcus, Influenza bacteria, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, etc. from cattle and pigs. This product can diffuse into bacterial cells through liposolubility, mainly acting on the 50s subunit of the 70s ribosome of bacteria, inhibiting the growth of peptidase and inhibiting the formation of peptide chains, thereby preventing protein synthesis and achieving antibacterial purposes. This product has rapid oral absorption, wide distribution, long half-life, high blood drug concentration, and long blood drug maintenance time.