Preparation of acetophenone

Install an electric stirrer, thermometer, drip funnel, and condenser tube on a 250mL four port flask. Install a calcium chloride drying tube at the upper end of the condensing tube, which is then connected to a hydrogen chloride gas absorption device. Add 39g (0.5mol) of anhydrous benzene and 40g (0.3mol) of crushed anhydrous aluminum chloride to a four necked bottle, and add 25g (0.25mol) of acetic anhydride dropwise with stirring. At this point, cool the four necked bottle with cold water and add acetic anhydride for about 30 minutes. In order to complete the reaction, acetic anhydride was added dropwise. Heat at 70-80 ℃ for 45 minutes. After cooling, pour the reactants into 100g of ice water. If aluminum hydroxide precipitates are generated, concentrated hydrochloric acid can be used to dissolve the precipitate and then separate out the benzene layer. 30mL for water layer × Extract 2% benzene, merge all benzene layer solutions, wash with 30mL of water, 30mL of 5% sodium hydroxide solution, and 30mL of water in sequence, and separate the benzene layer and dry it with anhydrous magnesium sulfate. Atmospheric distillation recovers benzene and collects fractions from 199 to 203 ℃, which is the product acetophenone .